Cap Sease has a BA in anthropology from Bryn Mawr College and a graduate degree in archaeological conservation from the University of London. In 1977, she joined the staff of the Metropolitan Museum of Art in New York where she was conservator in charge of the installation of the Michael Rockefeller Wing of archaeological and ethnographic art. She then ran a private practice in New York until joining the staff of the Field Museum of Natural History in Chicago in 1986, where she was the head of the Division of Conservation. Although her primary responsibility was to the anthropology collections, she served as consultant to the other natural history divisions and was actively involved in the exhibition of all collections. After 15 years at the Field Museum, she moved to the Peabody in December 2000. Throughout her career, she has been the conservator on numerous archaeological excavations in the Mediterranean and the Middle East, including three separate excavations in Iraq.